68

Ashwagandha

Adaptogenic Herb

Premier adaptogen for stress reduction and hormonal balance. Reduces cortisol and supports testosterone.

Onset2wk
Duration1mo
Half-life6h
Safety8/10

Effects Profile

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Dosage & Timing

Dosage Range

300

mg

600mg

1200

mg

Best time

Evening

Legal (US/EU)

OTC

Tips

  • Take in evening for sleep benefits
  • Effects build over 4-8 weeks
  • KSM-66 extract is most studied
  • Cycle 8 weeks on, 2 weeks off

Safety

Contraindications

  • Thyroid disorders (may increase T4)
  • Autoimmune conditions
  • Pregnancy

Side Effects

mild
moderate
severe
Drowsiness
0.1-1%
GI upset
0.1-1%

Mechanism

Modulates HPA axis, reduces cortisol, enhances GABA signaling, and supports thyroid function.