Bacopa Monnieri

Also known as: Brahmi, Water Hyssop

Ayurvedic

Adaptogen

Tier A

Meta-analysis of RCTs (n>500)

T1Full ProfileAdaptive

Traditional Ayurvedic herb with strongest evidence for memory enhancement. Requires 8-12 weeks for full effects. Take with fats for absorption.

Mechanism of Action

Contains bacosides that enhance synaptic communication. Increases dendritic length and branching. Antioxidant and acetylcholinesterase inhibition.

Contraindications

May cause fatigue - take with food or at night if problematic
Thyroid disorders (may affect thyroid hormones)

Performance Profile

Mood

Stress Resistance

Anxiety Reduction

Emotional Stability

Dosage

300mg

min

450mg

600mg

max

Timing

Best time

Morning

4 wk

onset

1 mo

duration

Half-life

4 hr

Safety & Legal

9/10

Well-tolerated

Legal Status

OTC

Mild

Moderate

Severe

Gastrointestinal upset

1-10%mild

Fatigue/drowsiness

1-10%mild

Dry mouth

0.1-1%mild