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CJC-1295 (with DAC)

Also known as: Modified GRF 1-29, DAC:GRF

Growth Hormone Secretagogue

Peptide
C

Tier C

Single RCT or lower-quality studies

T2Partial ProfilePeptide

Long-acting GHRH analog with Drug Affinity Complex for extended half-life. Promotes sustained GH release for muscle growth and fat loss.

Mechanism of Action

GHRH analog that stimulates GH release from pituitary. DAC modification extends half-life to ~8 days via albumin binding.

Contraindications

  • Cancer history (growth hormone concerns)
  • Diabetes (may affect insulin sensitivity)
  • Research chemical - not FDA approved
  • DAC version provides continuous (not pulsatile) GH elevation

Performance Profile

Sleep Quality
+3
Sleep Onset
+1
Deep Sleep
+3
Recovery Speed
+4

Dosage

1mg

min

2mg

4mg

max

Timing

Best time

Evening

1 hr

onset

1 wk

duration

Half-life
6 d

Safety & Legal

6/10

Generally safe

Legal Status

Unregulated

Mild
Moderate
Severe
Injection site reaction
1-10%mild
Water retention
1-10%mild
Flushing
0.1-1%mild
Headache
0.1-1%mild