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63

Lion's Mane

Also known as: Hericium erinaceus, Yamabushitake

Medicinal Mushroom

Adaptogen
B

Tier B

Multiple RCTs (n>100)

T2Partial ProfileAdaptive

Medicinal mushroom that stimulates NGF (Nerve Growth Factor) production for neurogenesis and cognitive enhancement. Requires 4+ weeks.

Mechanism of Action

Contains hericenones and erinacines that cross BBB and stimulate NGF synthesis. Promotes neuroplasticity and myelin regeneration.

Contraindications

  • Mushroom allergies
  • May interact with blood thinners

Performance Profile

Focus
+2
Memory
+4
Processing Speed
+1
Mental Clarity
+3
Creativity
+2
Learning
+4

Dosage

500mg

min

1000mg

3000mg

max

Timing

Best time

Morning

2 wk

onset

1 mo

duration

Half-life
12 hr

Safety & Legal

10/10

Well-tolerated

Legal Status

OTC

Mild
Moderate
Severe
Gastrointestinal discomfort
<0.1%mild
Skin rash (allergic)
<0.1%mild