Modafinil
Provigil, Modalert
Eugeroic
Nootropic
A
T1 Full
Acute
Unregulated Substance
Not FDA approved. Safety and efficacy not fully established. Consult a healthcare provider before use.
US: prescriptionEU: prescription
Wakefulness-promoting agent for cognitive enhancement. Works primarily through dopamine reuptake inhibition.
Mechanism of Action
Inhibits dopamine transporter (DAT), increasing extracellular dopamine. Also affects orexin and histamine systems.
Usage Tips
- Take early morning to avoid sleep disruption
- Stay well hydrated throughout the day
- Cycle usage to prevent tolerance (5 on, 2 off)
Contraindications
- Hypersensitivity to modafinil
- History of left ventricular hypertrophy
- Concurrent hormonal contraceptives
Performance Profile
Physical Energy
A+3
Mental Stamina
A+5
Alertness
A+5
Motivation
B+4
Dosage
50mg
min
100mg
200mg
max
Timing
Best time
Morning
1 hr
onset
10 hr
duration
Half-life
12 hrSafety & Legal
7/10
Generally safe
Legal Status
Prescription
US & EU
mild
moderate
severe
Headache
1-10%mild
Nausea
1-10%mild
Insomnia
>10%moderate
Anxiety
0.1-1%moderate