Omega-3 (EPA/DHA)

Also known as: Fish Oil, EPA, DHA

Essential Fatty Acids

Supplement

Tier A

Meta-analysis of RCTs (n>500)

T1Full ProfileDeficiency

Essential fatty acids crucial for brain health, inflammation reduction, and cardiovascular function. Most people are deficient.

Mechanism of Action

DHA is structural component of brain cell membranes. EPA reduces inflammatory cytokines. Both modulate cell signaling.

Contraindications

Anticoagulant therapy (may increase bleeding risk)
Fish/shellfish allergy (consider algae-based alternatives)

Performance Profile

Anti-Inflammation

Antioxidant

Cardiovascular

Liver Health

Metabolic Health

Dosage

1000mg

min

2000mg

4000mg

max

Timing

Best time

Anytime

2 wk

onset

1 mo

duration

Half-life

2 d

Safety & Legal

10/10

Well-tolerated

Legal Status

OTC

Mild

Moderate

Severe

Fishy aftertaste

1-10%mild

Gastrointestinal upset

0.1-1%mild

Easy bruising (high doses)

<0.1%mild